← Back to Blog
ComplianceMay 18, 202512 min read

How to Register Cosmetics in Brazil: The Complete Step-by-Step Guide (2025)

Everything you need to know about ANVISA cosmetic registration: Grau 1 vs Grau 2, required documents, costs, timeline, and common mistakes that delay approval.

Share:
This article is part of the ANVISA Cosmetics Compliance Guide. Read the complete guide for a step-by-step roadmap.

Do you need to register your cosmetics before selling in Brazil?

Yes. Every cosmetic product sold in Brazil must be either notified (Grau 1) or registered (Grau 2) with ANVISA before it can be legally marketed. There are no exceptions for e-commerce, dropshipping, or small quantities.

Importing without registration risks customs seizure, fines up to R$ 1.5 million, and permanent platform bans on Mercado Livre and Amazon Brazil.

Grau 1 (Notificação) vs Grau 2 (Registro): which one applies to you?

FactorGrau 1 (Notificação)Grau 2 (Registro)
Risk levelLow riskHigh risk
ProcessOnline notification, simplerFull registration, rigorous review
Government feeFree~R$ 2,500-5,000
Timeline6-12 months12-24 months
Product typesBasic skincare, makeup, perfume, shampoo, conditionerSunscreen, anti-acne, hair dye, anti-aging, baby products, antiperspirant
Testing requiredBasic safety assessmentAdditional efficacy tests (SPF, stability, etc.)

How to determine your product's grade:

  • Does it claim SPF or sun protection? → Grau 2
  • Does it treat acne, wrinkles, or hair loss? → Grau 2
  • Is it a hair dye or bleach? → Grau 2
  • Is it for babies or children under 3? → Grau 2
  • Is it a basic moisturizer, lipstick, or perfume? → Grau 1

Step 1: Prepare your documentation

Before starting the ANVISA process, gather these documents:

Required for both Grau 1 and Grau 2:

  • Complete ingredient list (INCI names, concentrations) — must match the final formula
  • Product Safety Report (PSR) — prepared by a qualified technical responsible (Responsável Técnico)
  • GMP certificate — ISO 22716 accepted, must be current and properly notarized
  • Portuguese label — all text must be in Portuguese per RDC 752/2022
  • Brazilian Responsible Technical Person (PTR) — a licensed pharmacist or chemist based in Brazil

Additional for Grau 2:

  • Efficacy test reports — SPF validation for sunscreens, stability testing
  • Clinical safety data — for products with active ingredients
  • Additional toxicological data — for products with restricted ingredients at higher concentrations

Step 2: Appoint a Brazilian PTR (Responsável Técnico)

This is mandatory for all foreign brands. Your PTR is the legal representative for your product in Brazil and their name appears on the label. Options:

OptionCostBest for
Hire a regulatory consultant as PTR$2,000-5,000/yearSmall brands, 1-10 SKUs
Partner with a Brazilian distributorNegotiated into marginBrands seeking local distribution
Set up a Brazilian subsidiary$10,000+Large brands with significant Brazil presence

Step 3: Submit your application

For Grau 1, submit through ANVISA's online notification system (Sistema de Notificação). For Grau 2, submit through the full registration system (Sistema de Peticionamento).

Key fields to complete:

  • Product name (must match the label exactly)
  • Complete INCI ingredient list with concentrations
  • Product category and intended use
  • Manufacturer information
  • PTR information
  • GMP certificate details

Step 4: Wait for technical review

ANVISA's review process includes:

  • Initial queue: 2-3 months (varies by backlog)
  • Technical evaluation: 3-6 months for Grau 1, 6-12 months for Grau 2
  • Complementation (if needed): +2-4 months per round

Common reasons for complementation:

  • Ingredient list doesn't match the PSR
  • Label doesn't comply with RDC 752/2022
  • GMP certificate is expired or not properly notarized
  • Missing PTR designation
  • Product claims trigger drug classification

Step 5: Receive your registration number

Once approved, you'll receive:

  • Grau 1: Notification number (starts with specific prefix)
  • Grau 2: Registration number (starts with specific prefix)

This number must appear on your product label before sale.

Total cost breakdown (realistic 2025 estimates)

Cost itemGrau 1Grau 2
Government feeFree~$400-800
PTR retainer (annual)$2,000-5,000$2,000-5,000
PSR preparation$500-2,000$1,000-3,000
Label translation/adaptation$300-800$300-800
GMP documentation$500$500
Additional testing$0$3,000-8,000
Consultant fees (full service)$3,000-7,000$5,000-12,000
Total per SKU$5,000-10,000$10,000-25,000

Money-saving strategies

  • Start with your hero SKU. Perfect the process with one product, then batch the rest
  • Stagger submissions by 2-3 weeks. Incorporate feedback from the first into subsequent applications
  • Negotiate volume rates. If you have 5+ SKUs, most consultants offer discounts
  • Partner with a distributor. They often absorb PTR costs in exchange for exclusivity

Timeline: what to expect

PhaseGrau 1Grau 2
Preparation1-2 months2-3 months
Initial review queue2-3 months2-3 months
Technical evaluation3-6 months6-12 months
Complementation (if needed)+2-4 months+2-4 months
Final approval1-2 weeks1-2 weeks
Total realistic6-12 months12-24 months

Common mistakes that delay approval

  1. Using English labels. All label text must be Portuguese. Not "mostly Portuguese" — 100%.
  2. Assuming EU/FDA compliance = ANVISA compliance. ANVISA has unique restrictions.
  3. Incomplete ingredient lists. "Fragrance" isn't enough — disclose allergens and restricted components.
  4. Drug claims on cosmetic labels. "Treats acne" pushes you into drug registration (2-3 years).
  5. Hiring a PTR without cosmetics experience. A general pharmacist won't know ANVISA's specific requirements.

Next steps

Don't navigate ANVISA registration alone. Use our free compliance checker to verify your ingredient list before you start the registration process — catching issues early saves months of delays.

Get Compliance Tips in Your Inbox

Once a week. No spam. Just updates on ANVISA, COFEPRIS, and market strategy.

Tags:
ANVISAregistrationBrazilcosmeticsstep-by-step

Check your products with CosmetCheck

Try Free
How to Register Cosmetics in Brazil: The Complete Step-by-Step Guide (2025) | CosmetCheck